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Summary. The objective of this study is to analyze the use of the fictions in the therapeutic relationships with terminal oncological patients recovered in hospice Valletta and to put some critical considerations about the application of the psychotherapy at the end of life as a neurotic fiction or as a curative model. In fact fictions with terminal patients protect them from a complex of inferiority and in psychotherapy unmasking fictional purposes could lead patients to get away from reality and discourage towards the goal of life.